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Table 2 Characteristics of non-QAACT available in the public sector during the most recent survey round

From: Do anti-malarials in Africa meet quality standards? The market penetration of non quality-assured artemisinin combination therapy in eight African countries

 

Kinshasa, DRC 2015

Katanga DRC 2015

Nigeria 2015

Kenya 2014

Tanzania 2014

Uganda 2015

Zambia 2014

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

N = 390

N = 148

N = 96

N = 50

N = 58

N = 59

N = 941

Active ingredients (type)

 Artemether lumefantrine

75.0 (69.9–79.5)

76.8 (66.1, 84.9)

76.2 (52.7, 90.2)

44.2 (23.4, 67.3)

52.6 (33.1, 71.4)

37.6 (22.1, 56.2)

100.0 (99.8, 100.0)

 Artesunate amodiaquine

4.9 (3.1, 7.9)

10.5 (3.9, 25.3)

8.3 (1.6, 33.0)

0.0 (–)

0.0 (–)

0.0 (–)

0.0 (–)

 Artesunate mefloquine

0.0 (–)

0.0 (–)

0.3 (<0.1, 2.2)

0.3 (0.1, 1.0)

5.0 (1.2, 18.0)

0.0 (–)

0.0 (–)

 Artemisinin piperaquine

1.2 (0.3, 4.5)

1.6 (0.5, 4.9)

0.0 (–)

6.4 (2.8, 13.9)

2.5 (1.0, 6.3)

0.0 (–)

0.0

 Artemisinin naphthoquine

0.9 (0.1, 6.1)

0.0 (–)

0.0 (–)

6.2 (2.6, 13.9)

0.0 (–)

19.0 (7.7, 39.7)

0.0 (–)

 Artesunate SP

5.1 (3.3, 7.9)

5.5 (2.9, 10.3)

3.2 (0.5, 18.8)

0.8 (0.2, 3.0)

0.0 (–)

0.0 (–)

0.1 (<0.1, 0.2)

 Dihydroartemisinin piperaquine

12.1 (8.2, 17.3)

2.1 (0.9, 4.7)

12.0 (4.4, 28.7)

42.1 (26.1, 59.9)

39.9 (22.0, 61.0)

43.0 (26.1, 61.6)

0.0 (–)

 Dihydroartemisinin SP

0.8 (0.4, 1.8)

3.5 (0.9, 12.3)

0.0 (–)

0.0 (–)

0.0 (–)

0.0 (–)

0.0 (–)

 Arterolane piperaquine

0.0 (–)

0.0 (–)

0.0 (–)

0.0 (–)

0.0 (–)

0.4 (0.1, 2.6)

0.0 (–)

Product formulation

 Tablet

56.5 (48.0, 64.7)

70.0 (61.4, 77.3)

61.0 (41.9, 77.2)

77.1 (64.5, 86.2)

91.5 (78.6, 96.9)

87.3 (74.7, 94.1)

99.6 (99.0, 99.8)

 Suspension

43.5 (35.3, 52.0)

30.0 (22.7, 38.6)

38.1 (22.1, 57.2)

22.9 (13.8, 35.5)

7.6 (2.6, 20.1)

12.8 (5.9, 25.3)

0.4 (0.2, 1.0)

 Granule

0.0 (–)

0.0 (–)

0.9 (0.1, 7.0)

0.0 (–)

0.9 (0.1, 5.6)

0.0 (–)

0.0 (–)

 

N = 384

N = 145

N = 96

N = 50

N = 54

N = 59

N = 939

Country of manufacturea

 Local

25.6 (19.8, 32.4)

23.7 (15.9, 33.7)

17.1 (5.2, 43.5)

14.8 (7.1, 28.2)

1.1 (0.2, 6.6)

0.0 (–)

0.0 (–)

 India

62.7 (57.2, 67.8)

69.7 (59.7, 78.1)

61.5 (42.8, 77.3)

58.8 (40.5, 75.0)

35.3 (18.2, 57.2)

37.7 (21.9, 56.5)

99.9 (99.7, 100.0)

 China

2.4 (0.9, 6.6)

1.8 (0.6, 5.7)

19.0 (7.9, 39.0)

16.7 (8.7, 29.5)

47.3 (27.7, 67.7)

54.1 (33.9, 73.0)

0.0 (–)

 European Country

3.4 (2.0, 5.6)

2.9 (1.3, 6.4)

0.3 (< 0.1, 2.2)

9.7 (5.5, 16.6)

16.3 (6.4, 35.6)

8.3 (2.8, 22.0)

0.1 (< 0.1, 0.4)

 Otherb

6.0 (2.7, 12.8)

1.9 (0.4, 9.3)

2.2 (0.4, 12.1)

0.0 (–)

0.0 (0)

0.0 (–)

0.0 (–)

 Registered with the National Drug Regulatory Authority

52.8 (44.0, 61.4)

19.3 (13.2, 27.2)

48.5 (26.9, 70.6)

33.6 (21.5, 48.2)

n/a

63.2 (43.5, 79.2)

1.6 (0.9, 3.0)

  1. Countries excluded include: Benin (n = 18 products) and Madagascar (n = 4 products)
  2. n/a Registration list not available in Tanzania for 2014
  3. a Excluding products with unknown country of manufacture
  4. b Kinshasa: Vietnam; Katanga: Morocco; Nigeria: Morocco, Pakistan