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Table 5 Multivariate mixed-effects logistic regression for dhfr and dhps mutations in ANC (pregnant women) and GP samples

From: Increase in the prevalence of mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates collected from early to late pregnancy in Nanoro, Burkina Faso

Fixed effect(s)

dhfr

dhps

N51

C59

S108

triple dhfr

S436

A437

OR

[95% CI]

p

OR

[95% CI]

p

OR

[95% CI]

p

OR

[95% CI]

p

OR

[95% CI]

p

OR

[95% CI]

p

Age

0.59

0.41

0.85

0.004

0.69

0.48

1.01

0.056

0.78

0.53

1.15

0.210

0.60

0.42

0.86

0.005

1.04

0.70

2.33

0.113

0.82

0.54

1.23

0.334

Seasona

1.07

0.70

1.65

0.758

1.06

0.68

1.67

0.795

1.04

0.65

1.65

0.877

1.05

0.69

1.60

0.821

1.46

0.91

2.33

0.113

0.73

0.43

1.22

0.225

Visitb

2.02

1.33

3.06

0.001

1.87

1.21

2.89

0.005

2.06

1.30

3.25

0.002

1.89

1.26

2.84

0.002

1.70

1.11

2.58

0.014

1.14

0.70

1.87

0.602

VisitXage

1.70

1.15

2.52

0.008

1.30

0.87

1.95

0.206

1.11

0.73

1.69

0.628

1.70

1.16

2.50

0.007

0.83

0.55

1.25

0.369

1.12

0.72

1.75

0.612

 Age in GP samples

1.01

0.86

1.18

0.931

0.90

0.77

1.06

0.210

0.87

0.73

1.03

0.098

1.03

0.89

1.19

0.723

1.46

0.91

2.33

0.113

0.92

0.78

1.08

0.293

  1. Odds ratios (OR) with 95% CI and p values are presented (p values <0.05 in italic)
  2. alow transmission season = 0, high transmission season = 1
  3. bANC booking = 0, GP = 1; age centred at 25 years