Table 4 Median time to 50 and 90% parasite reduction and recurrent infections up to day 28 (Study 1)
Group | 1A | 1B | 1C | 1D |
|---|---|---|---|---|
N | 34 | 30 | 30 | 19 |
Median time (h) to 50% parasite reduction (95% CI) | 18.0 (12.0–24.0) | 18.0 (6.0–24.0) | 9.0 (6.0–18.0) | 24.0 (12.0–24.0) |
Median time (h) to 90% parasite reduction (95% CI) | 30.0 (18.0–30.0) | 24.0 (12.0–36.0) | 30.0 (18.0–30.0) | 24.0 (24.0–30.0) |
Recurrences | 14 | 13 | 15 | 8 |
PCR data available | 12/14 | 11/13 | 10/15 | 8/8 |
New infection | 9 (75%) | 6 (54.5%) | 6 (60%) | 0 |
Recrudescences | 3 (25%) | 5 (45.5%) | 4 (40%) | 8 (100%) |