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Table 1 Four-day suppressive test: activity of hydroalcoholic crude root extract of Indigofera spicataon level of parasitemia and survival time of mice infected with Plasmodium berghei

From: Antiplasmodial activity of Indigofera spicata root extract against Plasmodium berghei infection in mice

Group

Level of parasitemia

Percent suppression

Survival date

NS

29.2 ± 1.85

6.6 ± 0.89

200 mg/kg IS

24.2 ± 1.24

17.12

7.2 ± 0.84

400 mg/kg IS

19.0 ± 1.22a,3

34.93

8.0 ± 0.71

600 mg/kg IS

13.6 ± 1.29a,3,b,3

53.42

8.8 ± 0.84a,2,b,1

25 mg/kg CQ

0.6 ± 0.4a,3,b,3,c,3,d,3

89.04

>14.6 ± 0.89a,3,b,3,c,3,d,3

  1. Data are expressed as mean ± SEM; n = 5
  2. IS, Indigofera spictata; CQ, chloroquine
  3. aCompared to control
  4. bTo 200 mg/kg
  5. cTo 400 mg/kg
  6. dTo 600 mg/kg
  7. 1p < 0.05
  8. 2p < 0.01
  9. 3p < 0.001