Table 4 Performance of gametocyte-specific RT-PCR markers against field samples from Uganda
Gametocytes/mL | n | pfs25 | PF3D7_0630000 | PF3D7_0816800 |
|---|---|---|---|---|
Sensitivity (95% CI) | ||||
 1–100 (n = 20) | 20 | 100% (83.2–100.0%) | 95.0% (75.1–99.9%) | 40.0% (19.1–64.0%) |
 101–1000 (n = 13) | 13 | 100% (75.3–100.0%) | 100.0% (75.3–100.0%) | 61.5% (31.6–86.1%) |
 >1000 (n = 14) | 14 | 100% (76.8–100.0%) | 100.0% (76.8–100.0%) | 100.0% (76.8–100.0%) |
 All samples (n = 74) | 74 | 100% (92.5–100.0%) | 97.9% (88.7–100.0%) | 63.8% (48.5–77.3%) |
Specificity (95% CI) | ||||
 All samples (=74) | 74 | 100% (87.2–100.0%) | 85.2% (66.3–95.8%) | 100.0% (87.2–100.0%) |