Skip to main content

Table 2 Notable P. vivax genes with their associated positive selection statistics

From: Genome-wide scans for the identification of Plasmodium vivax genes under positive selection

Gene and product description |iHS| XP-EHH \(\hat{\pi }\)
Mosquito transmission
 PVX_095475, circumsporozoite and TRAP-related (CTRP) 4.9995   0.0053
 PVX_118360, TRAP-like protein (TREP) 6.1642   0.0011
Red blood cell invasion
 PVX_099980, merozoite surface protein 1 (MSP1) 6.1512   0.0185
 PVX_099975, merozoite surface protein 1 paralog (MSP1P) 5.9582 1.9937 0.0036
 PVX_092975, merozoite adhesive erythrocytic binding (MAEBL) 6.1795   0.0024
 PVX_097575, tryptophan-rich antigen 6.9579   0.0082
 PVX_092275, apical membrane antigen 1 (AMA1) 5.1501   0.0056
 PVX_117880, rhoptry neck protein 2 (RON2) 6.4102   0.0027
 PVX_003845, serine-repeat antigen 4 (SERA4) 6.7713   0.2834
 PVX_121920, reticulocyte binding protein 2a (RBP2a) 4.7869 1.9589 0.0004
 PVX_081270, reticulocyte binding protein 2b (RBP2b) 6.3732   0.0036
 PVX_090325, reticulocyte binding protein 2c (RBP2c) 5.7962   0.0353
Drug resistance
 PVX_087980, chloroquine resistance transporter (CRT) 4.9064   0.0024
 PVX_118062, chloroquine resistance marker protein 7.2833 1.8212 0.0119
 PVX_118100, multidrug resistance protein 2 (MDR2) 5.3704 1.8858 0.0093