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Table 2 Notable P. vivax genes with their associated positive selection statistics

From: Genome-wide scans for the identification of Plasmodium vivax genes under positive selection

Gene and product description

|iHS|

XP-EHH

\(\hat{\pi }\)

Mosquito transmission

 PVX_095475, circumsporozoite and TRAP-related (CTRP)

4.9995

 

0.0053

 PVX_118360, TRAP-like protein (TREP)

6.1642

 

0.0011

Red blood cell invasion

 PVX_099980, merozoite surface protein 1 (MSP1)

6.1512

 

0.0185

 PVX_099975, merozoite surface protein 1 paralog (MSP1P)

5.9582

1.9937

0.0036

 PVX_092975, merozoite adhesive erythrocytic binding (MAEBL)

6.1795

 

0.0024

 PVX_097575, tryptophan-rich antigen

6.9579

 

0.0082

 PVX_092275, apical membrane antigen 1 (AMA1)

5.1501

 

0.0056

 PVX_117880, rhoptry neck protein 2 (RON2)

6.4102

 

0.0027

 PVX_003845, serine-repeat antigen 4 (SERA4)

6.7713

 

0.2834

 PVX_121920, reticulocyte binding protein 2a (RBP2a)

4.7869

1.9589

0.0004

 PVX_081270, reticulocyte binding protein 2b (RBP2b)

6.3732

 

0.0036

 PVX_090325, reticulocyte binding protein 2c (RBP2c)

5.7962

 

0.0353

Drug resistance

 PVX_087980, chloroquine resistance transporter (CRT)

4.9064

 

0.0024

 PVX_118062, chloroquine resistance marker protein

7.2833

1.8212

0.0119

 PVX_118100, multidrug resistance protein 2 (MDR2)

5.3704

1.8858

0.0093