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Table 4 Summary of drug resistance allele frequencies

From: Surveillance for sulfadoxine-pyrimethamine resistant malaria parasites in the Lake and Southern Zones, Tanzania, using pooling and next-generation sequencing

Region District Health centre Samples (N) Mutant, % (number of mutant/total sequences)
dhps540 dhps581 dhfr164
Lake Zone
 Kagera Karagwe Kayanga 120 89% (154,320/173,457) 24.9% (46,056/185,117) 0.6% (3972/623,835)
 Kagera Muleba Kaigara 120 91.2% (270,373/296,323) 1% (31,77/313,669) 0% (123/286,155)
 Mara Musoma Murangi 117 86% (160,431/186,561) 0% (24/196,781) 0% (20/327,806)
 Mara Tarime Sirari 120 98.4% (262,461/266,632) 0% (71/285,418) 0% (17/249,213)
 Geita Geita Katoro 122 97.2% (254,986/262,202) 0.2% (547/280,267) 0% 19/310,706)
 Geita Nyang’hwale Kharumwa 120 92.9% (176,055/189,500) 2.4% (4860/201,156) 0% (23/322,015)
 Mwanza Misungwi Misasi 130 92.7% (168,879/182,105) 2% (3773/193,348) 0% (15/348,488)
 Mwanza Sengerema Mwangika 121 93.2% (177,559/190,591) 0.3% (692/202,087) 0% (24/386,750)
Mean allele frequency Lake Zone* 970 82.6% 3.9% 0.1%
Southern Zone
 Lindi Lindi Rural Kitomanga 124 94.4% (162,087/171,760) 0% (47/177,058) 0% (11/225,710)
 Lindi Nachingwea Marambo 129 77.3% (35,351/45,753) 0.1% (57/50,926) 0% (41/231,375)
 Mtwara Masasi Nagaga 160 68.1% (107,370/157,670) 0% (17/164,456) 0% (46/247,292)
 Mtwara Mtwara Nanguruwe 129 73.2% (104,952/143,305) 0.8% (1180/154,626) 0% (17/385,082)
 Ruvuma Songea Madaba 120 92% (71,494/77,751) 0% (11/83,706) 0% (13/324,890)
 Ruvuma Namtumbo Namtumbo 118 55.7% (26,134/46,901) 0% (12/52,484) 0% (22/318,552)
Mean allele frequency Southern Zone* 780 76.8% 0.2% 0%
  1. * Mean allele frequency for each zone was calculated by averaging the percentage of mutants from each health center