Table 3 Frequency of G6PD genotypes in different regions in Brazil
From: G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon
State | Region | Study location | Study population | N individuals | G6PDd (n) | G6PDd (%) | A− variant | A+ variant |  | Mediterranean | Seatle | SantaMaria | Others | References |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs1050828 (G202A) | rs1050829 (A376G) | rs1050828 (G202A) | rs5030868 (C563T) | rs137852318 (G844C) | rs5030872 (A542T, A376G) | |||||||||
Males/females | rs1050829 (A376G) | Â | Â | Â | Â | Â | ||||||||
Acre | Alto do Juruá | Community | Adult males | 516 | 23 | 4.46 | 22 | 1 |  |  |  |  |  |  |
Acre | Acrelândia | Home visits | Children (<10 years of age) | 1104 | 98 | 8.9 |  |  |  |  |  |  |  | Cardoso et al. [26] |
Amazonas | Manaus | Community | Ismail Aziz Community | 200 | 6 | 3.0 | 5 | 0 | 0 | 0 | Â | Â | 1 | Santana [20] |
Amazonas | Manaus | Community | Adult males | 1478 | 66 | 4.5 | 56 | 0 | 0 | 10 | Â | Â | Â | Santana [21] |
Bahia | Salvador | Hospital | Neonates | 655 | 66 | 8.3/11.6 | 54 | 2 | 2 | Â | Â | Â | 5 | Neto et al. [27] |
Pará | Belém | Hospital | G6PD deficient | 196 | 196 | NA | 161 | 14 | 0 | 0 | 9 | 5 | 5 | Hamel [13] |
Piauà | Teresina | Community | Adult population | 62 | 4 | 10/4.8 |  |  |  |  |  |  |  | Ferreira et al. [28] |
Rio Grande do Norte | Natal | Hospital | Newborns | 400 | 8 | 3.9/0 | 8 | Â | Â | Â | Â | Â | Â | Iglessias et al. [29] |
Rio Grande do Sul | Porto Alegre | Hospital | Suspected G6PD deficient | 348 | 36 | 10.3 | 34 | Â | Â | Â | Â | Â | Â | Castro [30] |
Rio Grande do Sul | Rio Grande do Sul | Hospital | Newborns | 2799 | 217 | 8.6/7.0 | Â | Â | Â | Â | Â | Â | Â | Castro [31] |
Rio Grande do Sul | Porto Alegre | hospital | Newborns (50% presenting jaudice) | 490 | 22 | 4.5 | 14 | Â | Â | 0 | Â | Â | 8 | Carvalho [32] |
Rio Grande do Sul | Porto Alegre | Hospital | Patients with jaudice | 173 | 14 | 8.7 | Â | Â | Â | Â | Â | Â | Â | Giovelli et al. [33] |
Rondônia | Porto Velho | Diagnostic Center | Malaria suspected cases | 122 | 4 | 5.8/0 |  |  |  |  |  |  |  | Katsuragawa [34] |
São Paulo | Campinas | Hospital | G6PD deficient | 150 | 150 | NA | 146 | 0 | 0 | 3 |  |  | 1 | Saad [37] |
São Paulo | Bragança Paulista | Hospital | Adult males-blood donors | 4621 | 80 | 1.7 |  | Not investigated | 79 | 0 |  |  |  | Compri [35] |
São Paulo | São Paulo | Community | Adult males | 373 | 15 | 4.0 | 12 | 0 | 0 | 0 | 2 |  | 1 | Oliveira [12] |
São Paulo | Araraquara | Hospital | Adult males-blood donors | 5087 | 89 | 1.7 | 86 | 0 | 0 | 3 |  |  |  | Ferreira et al. [38] |
São Paulo | Bauro | Health Centre | Children males | 2657 | 97 | 3.7 |  |  |  |  |  |  |  | Nicolielo et al. [36] |