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Fig. 3 | Malaria Journal

Fig. 3

From: Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen

Fig. 3

Humoral anti-PbCS responses in immunized mice. a Kinetics of anti-PbCS IgG responses elicited in mice immunized with 30, 150 and 300 YU of N-PbCS non-adjuvanted yeast lysates. Curves represent group mean value with SEM. OD450nm are expressed in log10 scale. “x3”—three bi-weekly immunizations; “x5”—five weekly immunizations. Mouse sera were analysed at 1/103 dilution. b Isotyping of humoral IgG responses at day 42 in mice immunized with 30, 150, and 300 YU of N-PbCS non-adjuvanted yeast lysates. Bars correspond to median values per group. Asterisks indicate significant median differences (one symbol for p < 0.05, Mann–Whitney nonparametric test). Antibody titer of the non-parasitized mouse is encircled

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