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Table 1 Efficacy results

From: New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model

Vaccine Protectiona Protected mice/total mice (% protected) Statistical analyses
p value
Study 1 Study 2 Study 3 Total Total vs. Null Total vs. DNA-HuAd5
DNA-HuAd5 5/14 (36%) 2/14 (14%) 3/14 (21%) 10/42 (24%) 0.0011b
DNA-GC44 6/14 (43%) 6/14 (43%) 0.0159c 1.000c
DNA-GC45 2/14 (14%) 2/14 (14%) 0.4815c 0.3845c
DNA-GC46 7/14 (50%) 5/14 (36%) 13/14 (93%) 25/42 (60%) <0.0001b 0.0018b
Null 0/14 (0%) 0/14 (0%) 0/14 (0%) 0/42 (0%)  
Naïve 0/14 (0%) 0/14 (0%) 0/14 (0%) 0/42 (0%)   
  1. aThe number and percentage of mice protected in each study, as well as the total number and percentage of mice protected in all three studies is presented. Statistical analyses (two-tailed Fisher’s Exact Test) utilized data from all three studies (n = 42)b or data from protection study 1 (n = 14)c