Table 5 Analysis of genetics effect on malaria treatment outcome (risk of recrudescence) in pregnant women

CYP2B6*6

 CYP2B6*1/*1

35

1

2.8

 CYP2B6*1/*6

32

2

6.5

 CYP2B6*6/*6

11

1

9.0

CYP2B6*18

 CYP2B6*1/*1

72

5

6.9

 CYP2B6*1/*18

14

2

14.2

 CYP2B6*18/*18

1

0

0

CYP3A4*1B

 CYP3A4*1/*1

2

1

50

 CYP3A4*1/*1B

37

3

8.1

 CYP3A4*1B/*1B

49

3

6.1

CYP3A5*3

 CYP3A5*1/*1

48

3

6.2

 CYP3A5*1/*3

36

3

8.3

 CYP3A5*3/*3

2

1

50

CYP3A5*6

 CYP3A5*1/*1

57

4

7.0

 CYP3A5*1/*6

26

3

11.5

 CYP3A5*6/*6

5

0

0

CYP3A5*7

 CYP3A5*1/*1

66

7

10.6

 CYP3A5*1/*7

20

0

0

 CYP3A5*7/*7

–

–

–

ABCB1 rs3842

 A/A

12

0

0

 A/G

25

3

12

 G/G

51

4

7.8