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Fig. 1 | Malaria Journal

Fig. 1

From: In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36

Fig. 1

Inhibition of ItG binding to ICAM-1 under static (a) and flow (c) conditions. Binding in the absence of mAb (control) and after pre-incubation with αICAM-1 mAb at 5 µg/ml for 1 h. b Inhibition of C24 binding to CD36 under static and d flow conditions. Binding in the absence of mAb (control) and after pre-incubation with αCD36 mAb at 10 µg/ml for 1 h. Reversal of ItG binding to ICAM-1 (e) and C24 binding to CD36 (f) under static conditions. pRBC were allowed to bind to the protein for 1 h and binding was determined after subsequent incubation with 5 µg/ml αICAM-1 mAb (e) or with 10 µg/ml αCD36 mAb (f) for 1 h. Results expressed as mean bound pRBC/mm2 ± standard deviation. Control: without antibody

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