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Fig. 4 | Malaria Journal

Fig. 4

From: In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36

Fig. 4

Reversal of ItG binding on TNF-stimulated HDMEC under flow conditions. pRBC were allowed to bind to the EC under flow for 5 min, washed for 2 min and then a solution of BB without mAb (control) or with 5 µg/ml αICAM-1 mAb, 10 µg/ml αCD36 mAb and a combination of both mAbs were used to reverse binding. The number of bound pRBC was counted at 0, 5, 10, 15 and 20 min. Results expressed as mean bound pRBC/mm2 ± standard deviation

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