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Fig. 5 | Malaria Journal

Fig. 5

From: In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36

Fig. 5

Reversal of binding of the culture-adapted clinical isolates, P069, 8146 and GL6, on unstimulated and TNF-stimulated HDMEC under static conditions. pRBC, including ItG, were allowed to bind for 1 h to the EC, washed and subsequently incubated in BB without mAb (control) or with αICAM-1 mAb at 5 µg/ml and αCD36 mAb at 10 µg/ml or the combination of these mAbs for 1 h. Results expressed as bound pRBC/mm2 ± standard deviation. **P < 0.01 (compared with group “with TNF”). Binding is also shown to unstimulated (“without TNF”) HDMEC

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