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Fig. 6 | Malaria Journal

Fig. 6

From: In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36

Fig. 6

Reversal of GL6 (a), P069 (b) and 8146 (c) binding on TNF-stimulated HDMEC under flow conditions. pRBC were allowed to bind to the cells under flow for 5 min, washed for 2 min and then a solution of BB without mAb (control) or with 5 µg/ml αICAM-1 mAb, 10 µg/ml αCD36 mAb or a combination of both was used for to reverse binding. The number of bound pRBC was counted at 5, 10, 15 and 20 min and expressed as percentage (%) bound pRBC/mm2 compared to 0 min. *P < 0.05 (compared to 0 min); **P < 0.01 (compared to 0 min)

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