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Fig. 2 | Malaria Journal

Fig. 2

From: Vector control with driving Y chromosomes: modelling the evolution of resistance

Fig. 2

\(P_{Mut}\) (black lines), P 1 (red lines), and P con (blue lines) for resistant cost-free mutations. a Probabilities \(P_{1}\) and P Mut increase with increasing uN 0, for R m  = 6 and m = 0.95 (solid lines) or R m  = 12 and m = 0.98 (dotted lines). b All probabilities increase with increasing R m , for m = 0.95 (solid lines) and \(m = 0.98\) (dotted lines), with uN 0 = 1. Curves only extend as far as R m  = 1/[2(1 − m)(1 − u)] (see Additional file 1: end of Section A1.1b) above which the strength of Y drive m < m crit and population elimination does not occur. c Probabilities decrease with increasing \(m\) (strength of Y drive), for R m  = 6, uN 0 = 1. d Probabilities increase with increasing mutant fitness parameter w, for \(R_{m} = 6,m = 0.95\) (solid lines) and \(R_{m} = 12,m = 0.98\) (dotted lines), and \(uN_{0} = 1\). The deterministic model shows that the population will be eliminated for w ≤ 0.563 for m = 0.95, and for \(w \le 0.452\) for m = 0.98. For all plots, h 0 = 0.05. Error bars at low \(R_{m} , w\) and high m show the standard error for simulations (averaged over \(10^{6}\) runs, N 0 = 106), when the branching process model does not apply; if not shown, error is within thickness of plot line

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