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Table 1 Performance comparison of P-Genus FISH and Giemsa microscopy against qRT-PCR for the detection of malaria parasites in clinical samples

From: Comparative evaluation of fluorescent in situ hybridization and Giemsa microscopy with quantitative real-time PCR technique in detecting malaria parasites in a holoendemic region of Kenya

  Sensitivity  % (95% CI) Specificity  % (95% CI) Predictive value Likelihood ratio Methods agreement  % K-value
Positive test  % (95% CI) Negative test  % (95% CI) Positive test  % (95% CI) Negative test  % (95% CI)
P-Genus FISH 29.3 (23.8–35.3) 75.8 (69.9–81.1) 56.0 (47.1–64.5) 50.5 (45.3–55.8) 1.21 (0.90–1.62) 0.93 (0.84–1.04) 52.0 0.051
Microscopy 58.2 (51.9–64.3) 93.0 (89.1–95.9) 89.8 (84.1–93.9) 68.0 (62.7–72.9) 8.35 (5.22–13.37) 0.45 (0.39–0.52) 75.2 0.508
  1. CI confidence interval, P-Genus FISH Plasmodium genus fluorescent in situ hybridization, K-value kappa value