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Fig. 5 | Malaria Journal

Fig. 5

From: Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana

Fig. 5

Seroprevalence of anti-Pfs48/45.6C and Pfs230-C0Ll antibodies. a The proportion of young children (0–5 years), older children (6–17 years) and adults (above 17 years) who were seropositive for Pfs48/45 and Pfs230 using L. lactis expressed Pfs48/45-6C and Pfs230-C0Ll antigens. Antibody responses to Pfs48/45-6C (b) and Pfs230-C0LI (c) were categorized as low (≤twofold higher than the negative control cutoff, medium (between two and fourfold higher than the negative control cutoff) or high (≥fourfold higher than the negative control cutoff). The percentage of young children, older children and adults that were seropositive with low, medium and high antibody levels against Pfs48/45-6C (b) or Pfs230-C0Ll (c) were plotted. The exact number of patients sampled in each age group is listed in Additional file 2: Table S2

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