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Fig. 6 | Malaria Journal

Fig. 6

From: Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana

Fig. 6

Antibodies titers against L. lactis expressed Pfs48/45-6C (a) and Pfs230C0Ll (b) antigens, respectively in the total study population. An ELISA was used to test recombinant antigens for reactivity with serum from malaria infected children and adults living in the Central Region of Ghana. All serum samples (1:200 dilution) were tested in duplicate and repeated at least twice. Optical densities (OD) for the serum samples were obtained from each ELISA plate and transformed into IgG concentrations (ng/μl) based on the regression curve obtained from titrating purified human polyclonal IgG (PB055, The Binding Site) on the corresponding plate. The graph shows the geometric mean of the antibody concentrations plus or minus the 95% confidence interval. The exact number of patients sampled in each age group is listed in Additional file 2: Table S2

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