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Table 5 Results for AQSP and the WHO-recommended ACT medicines

From: Comparison of anti-malarial drug efficacy in the treatment of uncomplicated malaria in African children and adults using network meta-analysis

Rank probabilities

Treatments

Odds ratios

95% CrI

Rank 1

Rank 2

Rank 3

AL

–

–

0

10−5

10−4

AQSP

0.87

0.50–1.51

0.0004

10−4

0.005

ASAQ

1.12

0.82–1.54

0.00

10−4

0.007

ASMQ

1.20

0.52–2.80

0.0016

0.05

0.08

ASSP

1.35

0.71–2.58

0.01

0.05

0.10

DHAP

1.92

1.29–2.83

0.04

0.20

0.30

  1. A total of 76 studies were analysed using the random effect model 2 under the hypothesis of consistency. Treatments were numbered as the first six combinations. Posterior distributions of odds ratio and 95% credible intervals (CrI) were extracted. AL was the comparator. Posterior rank probabilities are given for ranks 1, 2 and 3. In this model, DHAP was shown to be the most efficacious among the combination therapies
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Malaria Journal

ISSN: 1475-2875

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