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Table 2 Genotype and allele frequencies of the studied host gene polymorphisms

From: Prevalence of polymorphisms in glucose-6-phosphate dehydrogenase, sickle haemoglobin and nitric oxide synthase genes and their relationship with incidence of uncomplicated malaria in Iganga, Uganda

G6PD c.202 G>A

(n = 423)

HBB c.20 A>T

(n = 414)

NOS2 −954 G>C

(n = 411)

 

Frequency

N (%)

 

Frequency

N (%)

 

Frequency

N (%)

Females

 Wild type

158 (37.4)

Wild type, AA

303 (73.2)

Wild type

340 (82.7)

 Heterozygous

69 (16.3)

Heterozygous, AS

110 (26.6)

Heterozygous

66 (16.1)

 Homozygous

4 (1.0)

Homozygous, SS

1 (0.2)

Homozygous

5 (1.2)

Males

 Wild type

169 (39.9)

    

 Hemizygous

23 (5.4)

    

Allele frequency

 G

0.88

A

0.86

G

0.91

 A

0.12

T

0.14

C

0.09