Skip to main content

Table 7 Frequency of molecular markers associated with resistance of Plasmodium falciparum to SP and AQ in the districts of Kita and Bafoulabe during the pre- and post-intervention surveys

From: Measuring the impact of seasonal malaria chemoprevention as part of routine malaria control in Kita, Mali

  Kita Bafoulabe p
n/N % n %  
Pre-intervention (July 2014)
 dhfrN51I 38/48 79.2 50/58 86.2 0.42
 dhfrC59R 39/48 81.2 54/58 93.1 0.07
 dhfrS108 N 42/48 87.5 53/58 91.4 0.59
 Triple dhfr (N51I, C59R, S108N) 37/48 77.1 49/58 84.8 0.45
 dhps A437G 20/48 41.8 23/56 42.0 0.95
 dhps K540E 6/48 12.5 2/58 3.4 0.11
 Quintiple (triple dhfr+ dhpsA437G et K540E) 2/48 4.2 1/56 1.8 0.41
 Pfmdr1-86Y 8/42 19.0 13/54 24.1 0.60
 Pfcrt-76T 44/48 91.7 51/57 89.5 0.25
Post intervention (December 2014)
 dhfrN51I 38/38 100 79/79 100 1
 dhfrC59R 38/38 100 77/79 97.5 0.46
 dhfrS108N 37/38 97.4 68/78 87.2 0.10
 Triple dhfr (N51I, C59R, S108N) 37/38 97.4 66/78 87.2 0.10
 dhps A437G 25/38 65.8 35/79 44.3 0.01
 dhps K540E 1/38 2.6 5/79 6.3 0.47
 Quintuple (triple dhfr+ dhpsA437G et K540E) 1/38 2.6 1/78 1.8 0.60
 Pfmdr1-86Y 7/38 18.4 8/79 10.1 0.60
 Pfcrt-76T 28/38 73.7 59/78 75.6 0.81