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Table 2 Association between K13 mutations and day 3 parasite positivity

From: Clinical and molecular surveillance of artemisinin resistant falciparum malaria in Myanmar (2009–2013)

K13 mutation Number of isolates Total P
Day 3 negative Day 3 positive
T474I 2 0 2 1.000
M476V 1 0 1 1.000
C469F 2 4 6 0.004*
N490T 2 1 3 0.365
Y511H 1 0 1 1.000
G533A 4 1 5 0.531
G538V 5 1 6 0.597
N537I 4 5 9 0.004*
P553L 0 1 1 0.140
E556D 1 0 1 1.000
R561H 3 10 13 <0.0001*
P574L 14 5 19 0.166
C580Y 81 24 105 0.004*
F673I 1 3 4 0.010*
A675V 9 0 9 0.621
Total 130 55 185 <0.0001*
  1. * Significantly associated K13 mutation with day 3 parasite positivity after treatment with ACT
  2. Calculated by Chi square test and all other were calculated by Fisher’s exacted test with 95% CIs