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Fig. 3 | Malaria Journal

Fig. 3

From: Immunogenicity of the Plasmodium vivax merozoite surface protein 1 paralog in the induction of naturally acquired antibody and memory B cell responses

Fig. 3

Inhibitory activity of antibodies against PvMSP1P-19 binding to human erythrocytes. Seropositive plasma samples from acutely P. vivax-infected a high responders (n = 16) and b low responders (n = 13) were performed to evaluate the inhibitory activity of antibodies against PvMSP1P-19-erythrocyte binding. c The activity of the anti-PvMSP1P-19 inhibitory antibody against human erythrocyte binding in individuals (n = 5) in their acute phases and their recovery phases at 9 and 12 months after P. vivax infeciton. The transfected HEK293-T cells expressing PvMSP1P-19 were incubated with plasma and with human erythrocytes. The numbers of rosettes were compared between wells of transfected cells that were incubated with plasma of vivax malaria patients relative to the negative control well. The charts show the mean inhibition of each P. vivax subject. Error bars represent ± standard deviation

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