Plasmodium vivax genetic diversity and heterozygosity in blood samples and resulting oocysts at the Thai–Myanmar border

Table 2 Genetic diversity of P. vivax in patient blood samples (P) and oocysts (O) for six selected cases

Measure	Infection	Sample	N	Locus								Mean	SE
Measure	Infection	Sample	N	Pv3.27	Pv3.502	Pv8.504	MS5	MS6	MS7	MS8	MS16	Mean	SE
Number of alleles	Monoclonal	P	3	3	3	2	2	3	3	3	3	2.750	0.164
	Monoclonal	O	97	4	3	2	2	3	3	3	3	2.875	0.227
	Polyclonal	P	3	4	3	2	3	3	2	4	3	3.000	0.267
	Polyclonal	O	34	5	5	4	2	6	4	6	4	4.500	0.463
	All oocysts		131	7	6	5	5	6	6	8	6	6.125	0.927
Expected heterozygosity	Monoclonal	P	3	0.667	0.667	0.444	0.444	0.667	0.667	0.667	0.667	0.611	0.036
	Monoclonal	O	97	0.290	0.187	0.177	0.069	0.360	0.078	0.159	0.119	0.180	0.036
	Polyclonal	P	3	0.722	0.667	0.278	0.667	0.667	0.444	0.722	0.611	0.597	0.055
	Polyclonal	O	34	0.757	0.698	0.653	0.346	0.707	0.597	0.704	0.656	0.640	0.045
	All oocysts		131	0.527	0.354	0.436	0.301	0.474	0.406	0.433	0.492	0.428	0.069

Monoclonal and polyclonal infections are defined by initial blood stage results (see main text and Fig. 2)