Fig. 2

Ned-19 activity on different stages of the P. falciparum asexual cycle. Synchronized ring stage parasites (initial parasitaemia 1.4%) were used to yield subcultures, numbered 1–8, which were incubated with DMSO control (blue line) or exposed to 100 μM Ned-19 (red line) at different times of the parasite asexual cycle. a Stages of the parasite asexual cycle. Black arrows indicate times at which the cultures were sampled. b Histograms showing parasitaemia and distribution of the different parasite stages for the cultures in each time-point. ER early rings, LR late rings, ET early trophozoites, LT late trophozoites, ES early schizonts, LS late schizonts. A representative sample of these forms is shown in Additional file 2: Figure S2