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Table 2 Cox regression models with adjusted rate ratios of P. vivax infection for various risk factor levels

From: Proximity to vector breeding site and risk of Plasmodium vivax infection: a prospective cohort study in rural Ethiopia

  Model 1—no adjustments for ITN use fraction (n = 8121) Model 2—adjusted for ITN use fraction (n = 8096)
RR (95% CI) P value RR (95% CI) P value
Increasing household proximity to breeding sitea 1.50 (1.30–1.74) < 0.001 1.56 (1.34–1.81) < 0.001
Age at study entry
 ≥ 25 Ref   Ref  
 15–24 1.73 (0.89–3.36) 0.11 1.40 (0.69–2.83) 0.35
 5–14 4.71 (2.73–8.13) < 0.001 3.54 (1.95–6.43) < 0.001
 0–4 6.49 (3.64–11.55) < 0.001 5.47 (2.98–10.06) < 0.001
Gender
 Males Ref   Ref  
 Females 0.85 (0.61–1.18) 0.34 0.86 (0.62–1.20) 0.38
Persons living in household
 ≤ 7 Ref   Ref  
 ≥ 8 1.27 (0.92–1.77) 0.15 1.16 (0.83–1.63) 0.39
ITN use fraction (%)b
 > 50    Ref  
 ≤ 50    1.85 (1.20–2.83) 0.005
  1. aDistance to breeding site was categorized into: > 2700 m (ref); 2400–2700; 2100–2400; and < 2100 m, and modelled linearly
  2. bITN use was recorded weekly (starting from week 5) during the regular follow-up visits to households. Participants were asked if they slept under a ITN the night before the visit. Use fraction was calculated as the number of nights reportedly sleeping under a ITN divided by the total number of nights asked. For those with P. vivax infection, ITN use fraction was calculated only for weeks prior to infection