Skip to main content

Table 1 Effect of initial P. vivax stage on pLDH-ELISA IC50 results

From: Measuring ex vivo drug susceptibility in Plasmodium vivax isolates from Cambodia

Drug Spearman correlation test Mann–Whitney U test P value
for IC50 and EM ratio EM ratio ≥ 4 EM ratio ≤ 0.25
N coefficient P-value N median IC50 N median IC50
DHA 57 − 0.34* 0.009* 11 2.6 12 7.5* 0.008*
AS 56 − 0.46* < 0.001* 11 2.9 11 9.4* < 0.001*
CQ 46 − 0.12 0.445 12 23.8 4 28.1 0.716
PPQ 52 − 0.01 0.922 12 104.3 7 99.5 0.612
LUM 34 − 0.42* 0.014* 4 5.6 7 25.4* 0.023*
DOX 35 − 0.70* < 0.001* 5 12,680 9 42,667* 0.003*
ATM 23 − 0.12 0.593 3 0.61 7 2.0 0.137
MQ 27 − 0.39 0.046* 4 161.2 4 203.7 0.083
  1. * Statistical significance