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Table 2 Comparisons of antibody levels

From: Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens

Variable PM+ (n = 341) PM− (n = 1036) P-value AUC
FV2 FCR3 4820 (1360, 11,497) 1427 (426, 5553) < 0.0001 0.66
DBL1 + 2 FCR3 2195 (746, 5944) 829 (277, 3034) < 0.0001 0.65
DBL1 IT4 1261 (421, 3130) 476 (201, 1320) < 0.0001 0.66
DBL1 3D7 1258 (511, 3037) 571 (225, 1433) < 0.0001 0.65
DBL1 7G8 921 (392, 1925) 583 (249, 1250) < 0.0001 0.60
DBL2 FCR3 815 (410, 1737) 526 (189, 1275) < 0.0001 0.60
DBL3 FCR3 1286 (434, 4193) 625 (148, 2334) < 0.0001 0.62
DBL3 7G8 2126 (603, 6850) 717 (201, 3190) < 0.0001 0.65
DBL4 FCR3 2096 (617, 4960) 875 (229, 2757) < 0.0001 0.63
DBL4 7G8 1108 (384, 3383) 451 (161, 1522) < 0.0001 0.64
DBL5 FCR3 7987 (793, 19,534) 1031 (138, 10,278) < 0.0001 0.66
DBL5 3D7 3898 (620, 10,411) 718 (164, 5251) < 0.0001 0.66
DBL5 7G8 4940 (743, 12,478) 686 (178, 6776) < 0.0001 0.66
DBL6 FCR3 1277 (393, 3686) 494 (150, 1648) < 0.0001 0.64
DBL6 7G8 4389 (1766, 9280) 2274 (793, 5222) < 0.0001 0.64
ID1-ID2a FCR3 474 (212, 1475) 304 (120, 773) < 0.0001 0.61
ID1-ID2a 3D7 2089 (884, 3952) 1356 (490, 3243) < 0.0001 0.58
Number of domain recognized out of 6 2 (0, 3) 0 (0, 2) < 0.0001 0.64
Number of variants recognized out of 13 3 (0, 6) 0 (0, 4) < 0.0001 0.65
AMA-1 23,769 (17,479, 24,375) 14,621 (3597, 23,680) < 0.0001 0.70
CSP 398 (193, 891) 231 (137, 545) < 0.0001 0.62
EBA-175 17,755 (4388, 24,143) 5263 (731, 20,562) < 0.0001 0.66
LSA1 452 (158, 1833) 190 (71, 736) < 0.0001 0.63
MSP1 4851 (1045, 13,335) 1856 (450, 8148) < 0.0001 0.61
MSP2 11,432 (3751, 22,159) 3303 (805, 10,511) < 0.0001 0.69
MSP3 1069 (362, 4188) 413 (149, 1853) < 0.0001 0.63
MSP11 1629 (629, 4031) 681 (298, 1789) < 0.0001 0.66
Pf41 5214 (809, 17,004) 1654 (239, 8324) < 0.0001 0.63
Pf70 815 (470, 1478) 602 (294, 1093) < 0.0001 0.60
RESA 84 (49, 228) 73 (43, 179) 0.0095 0.55
  1. The data were summarized by median MFI with 25th and 75th percentiles
  2. AUC was based on univariate logistic regression models
  3. P-value was based on Wilcoxon-Rank-Sum test