Table 2 Influence of age and exposure on antibody levels to PfGPI in Papua New Guinean children
P. falciparum | P. vivax | |||||
|---|---|---|---|---|---|---|
n | Geom mean (95% CI)* | P value | n | Geom mean (95% CI)* | P value | |
Age (months) | ||||||
All children | ||||||
12–17 | 81 | 0.091 (0.074–0.111) | 0.53 | |||
18–23 | 49 | 0.083 (0.061–0.114) | ||||
24–29 | 38 | 0.117 (0.080–0.170) | ||||
30–35 | 45 | 0.108 (0.075–0.155) | ||||
36–41 | 10 | 0.081 (0.032–0.204) | ||||
PCR− | ||||||
12–17 | 55 | 0.076 (0.060–0.097) | 0.009 | 37 | 0.067 (0.051–0.087) | 0.221 |
18–23 | 22 | 0.053 (0.036–0.078) | 19 | 0.074 (0.043–0.128) | ||
24–29 | 14 | 0.160 (0.079–0.323) | 18 | 0.126 (0.086–0.185) | ||
30–35 | 16 | 0.113 (0.062–0.207) | 19 | 0.083 (0.047–0.146) | ||
36–41 | 4 | 0.155 (0.014–1.737) | 5 | 0.087 (0.049–0.156) | ||
PCR+ | ||||||
12–17 | 26 | 0.131 (0.090–0.192) | 0.43 | 44 | 0.118 (0.088–0.157) | 0.69 |
18–23 | 27 | 0.120 (0.078–0.186) | 30 | 0.090 (0.060–0.133) | ||
24–29 | 24 | 0.097 (0.062–0.153) | 20 | 0.109 (0.056–0.210) | ||
30–35 | 29 | 0.106 (0.065–0.170) | 26 | 0.131 (0.080–0.215) | ||
36–41 | 6 | 0.053 (0.018–0.154) | 5 | 0.075 (0.007–0.773) | ||
Infection status | ||||||
PCR− | 111 | 0.085 (0.070–0.103) | 0.084 | 98 | 0.081 (0.067–0.098) | 0.036 |
PCR+ | 112 | 0.108 (0.088–0.133) | 125 | 0.109 (0.089–0.134) | ||
Infection free | 51 | 0.061 (0.047–0.077) | 0.004 | |||
Pf and Pv co-infected | 65 | 0.107 (0.079–0.144) | ||||