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Table 1 Mass fragments of the most abundant ions for the detection of anti-malarials by LC–MS/MS

From: Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

Compound name

Precursor ion (m/z)

Product ion (m/z)

Amodiaquine

356.1

283.0

Artemisinin

282.0

162.9

Atovaquone

365.0

337.0

Chloroquine

320.1

247.1

Cycloguanil

252.1

58.0

Dihydroartemisinin

221.0

163.1

Lumefantrine

530.1

512.1

Mefloquine

379.1

361.1

N-Methyl-quinidine

339.1

160.0

Primaquine

260.1

243.1

Proguanil

254.0

170.0

Quinine

325.1

307.1