Skip to main content

Table 2 Diagnostic test performance of nPCR-saliva and nPCR-blood with thick film microscopy as reference standard in the diagnosis of malaria

From: Detection of Plasmodium falciparum DNA in saliva samples stored at room temperature: potential for a non-invasive saliva-based diagnostic test for malaria

Test characteristics NPCR-saliva NPCR-blood
Sensitivity [95%CI] 95% [85 to 99] 100% [94 to 100]
Specificity [95%CI] 93% [88 to 99] 87% [80 to 91]
PPV [95%CI] 83% [72 to 91] 72% [61 to 82]
NPP [95%CI] 98% [94 to 99] 100% [97 to 100]
PLR [95%CI] 14 [8 to 25] 7 [5 to 11]
NLR [95%CI] 0.06 [0.02 to 0.17] 0
Observed agreements 94% 90%
Kappa value 0.8 0.7
  1. PPV positive predictive values, NPP negative predictive values, PLR positive likelihood ratio, NLR, negative likelihood ratio