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Table 7 The top 35 over-transcribed genes with available descriptions, in wild insecticide resistant Anopheles funestus relative to the susceptible laboratory strain, FANG

From: Malaria vectors in the Democratic Republic of the Congo: the mechanisms that confer insecticide resistance in Anopheles gambiae and Anopheles funestus

Accession number

Log2FC

FC

Adjusted p-value (FDR)

Best-hit Blast2Go description

Best-hit PEST descriptions

EZ916542

3.07

8.4

4.6E−04

Ubiquitin c variant 2

Polyubiquitin-B

EZ976930

3.03

8.2

8.2E−05

Cuticular protein 49aa cg30045-pb

CPR113: cuticular protein RR-2 family 113

EZ967106

2.97

7.9

8.1E−05

–

Myosin heavy chain

EZ980273

2.96

7.8

1.4E−02

tbc domain-containing protein kinase-like protein

TBC domain-containing protein kinase-like protein

EZ973782

2.94

7.7

8.2E−05

Cytochrome p450 6a8

CYP6M3: cytochrome P450

EZ915918

2.89

7.4

1.3E−04

Actin

Actin, cytoplasmic

EZ979664

2.86

7.3

8.1E−05

CHYMOTRYPSIN 1

CHYM1: chymotrypsin-1

EZ915406

2.75

6.7

8.1E−05

Sorbitol dehydrogenase

d-xylulose reductase A

EZ918406

2.70

6.5

8.1E−05

Ubiquitin c variant 2

Polyubiquitin

EZ980370

2.53

5.8

5.9E−03

Slow border cells

CCAAT/enhancer binding protein (C/EBP), invertebrate

EZ917907

2.53

5.8

3.7E−04

Flightin

Flightin

EZ919993

2.52

5.8

8.7E−05

–

CPLCA3: cuticular protein 3 in CPLCA family

EZ925592

2.51

5.7

1.2E−04

–

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4

EZ915656

2.51

5.7

8.7E−05

Troponin c

Troponin C

EZ917820

2.41

5.3

6.4E−04

–

CPR125: cuticular protein RR-2 family 125

EZ916349

2.37

5.2

9.0E−05

Actin

Actin, cytoplasmic

EZ966655

2.36

5.1

4.4E−04

Transforming growth factor beta regulator 1

Uncharacterized protein

EZ920676

2.30

4.9

6.9E−04

 

Troponin T, fast skeletal muscle

EZ966156

2.28

4.8

8.8E−03

Muscle lim protein

Muscle LIM protein at 84B

EZ915396

2.24

4.7

1.2E−04

Sorbitol dehydrogenase

d-xylulose reductase A

EZ917325

2.18

4.6

1.2E−04

Regulator of microtubule dynamics protein 1-like

Regulator of microtubule dynamics protein 1-like

EZ920255

2.18

4.5

1.2E−04

–

Muscle LIM protein at 84B

EZ915403

2.15

4.4

1.2E−04

Sorbitol dehydrogenase

d-xylulose reductase A

EZ917889

2.09

4.3

1.3E−04

–

Flightin

EZ974390

2.04

4.1

2.9E−04

Stretchin-isoform d

Stretchin-isoform d

EZ920519

2.00

4.0

1.3E−04

–

Actin, cytoplasmic

EZ973962

1.99

4.0

2.9E−04

Dimeric dihydrodiol dehydrogenase

Dimeric dihydrodiol dehydrogenase

EZ915590

1.98

3.9

1.6E−04

Venom allergen

A5R1: antigen 5 related protein 1

EZ915515

1.98

3.9

1.5E−04

–

CPCFC1: cuticular protein CPCFC family (CPCFC1)

EZ924022

1.95

3.9

1.5E−04

Pupal cuticle

Pupal cuticle

EZ916170

1.95

3.9

1.4E−04

Stretchin-isoform d

Stretchin-isoform d

EZ915759

1.88

3.7

2.9E−04

–

GSTS1: glutathione S-transferase sigma class 1

EZ976897

1.87

3.7

1.6E−04

Leucine-rich repeat-containing protein 20-like isoform 1

Leucine-rich repeat-containing protein 20-like isoform 1

EZ973739

1.87

3.6

1.6E−04

Lysozyme c-4

LYSC4: C-Type Lysozyme

EZ915209

1.85

3.6

3.6E−04

Glutathione S-transferase

GSTS1: glutathione S-transferase sigma class 1

  1. The complete gene list is included as Additional file 1