Skip to main content

Table 1 Transmission-blocking effects of mouse antiserum produced by rPb51 immunization

From: Characterization of Pb51 in Plasmodium berghei as a malaria vaccine candidate targeting both asexual erythrocytic proliferation and transmission

 

Control mice

rPb51 immunized mice

Con-M1

Con-M2

Con-M3

rPb5-M1

rPb5-M2

rPb5-M3

Mosquitoes infected/dissected

47/50

49/50

48/50

38/50

39/50

35/50

Prevalence of infection (%)a

94

98

96

76

78

70

Mean prevalence (%)

96

74.7

Reduction in prevalence (%)b

     

21.3*

Oocyst intensityc

87.2

90.1

82.9

33.8

29.9

32.1

SEMd

6.7

6.7

6.8

4.5

3.6

4.4

Mean oocyst intensity

  

86.7

  

31.9*

Reduction in oocyst intensity (%)e

     

54.8

  1. * P < 0.001 for comparisons between the experimental group and the control group
  2. aThe prevalence of infection was calculated by the number of mosquitoes with oocysts/total mosquitoes dissected in each group × 100%
  3. bThe percent reduction of prevalence was calculated as % mean prevalencecontrol − % mean prevalence rPb51
  4. cMean number of oocysts per mosquito midgut
  5. dStandard error of the mean
  6. eThe percent reduction in oocyst intensity was calculated as (mean oocyst intensitycontrol − mean oocyst intensityrPb51)/mean oocyst intensitycontrol × 100%