Table 1 Plasmodium falciparum O-GlcNAcylated proteins identified by mass spectrometry
From: Identification of O-GlcNAcylated proteins in Plasmodium falciparum
UniProtKB (accession number) | Score | Coverage | Mass | Matches | Sequences | Full name | Confirmed by using sWGA | [Ref.] (biological model) |
|---|---|---|---|---|---|---|---|---|
Click-chemistry | ||||||||
ACT1_PLAF7 | 169 | 0.12 | 42,072 | 8 (7) | 4 (4) | Actin-1 | X | [27] (Xenopus laevis); [59] (human breast cancer cell line MCF7) |
ACT2_PLAF7 | 30 | 0.07 | 42,977 | 4 (4) | 3 (3) | Actin-2 | [59] (human breast cancer cell line MCF7) | |
ALF_PLAFA | 1566 | 0.36 | 40,479 | 39 (38) | 15 (14) | Fructose-bisphosphate aldolase | [60] (Rattus norvegicus) | |
CH60_PLAFG | 96 | 0.08 | 79,738 | 6 (3) | 5 (3) | Chaperonin CPN60, mitochondrial | [61] (rat pancreatic b-cell line Rin-m5f) | |
EF1A_PLAFK | 732 | 0.23 | 49,238 | 25 (21) | 10 (9) | Elongation factor 1-alpha | X | [27] (Xenopus laevis); [59] (human breast cancer cell line MCF7) |
ENO_PLAFA | 694 | 0.18 | 49,015 | 20 (16) | 8 (5) | Enolase | [27] (Xenopus laevis); [59] (human breast cancer cell line MCF7); [60, 62] (Rattus norvegicus) | |
GRP78_PLAFO | 1864 | 0.27 | 72,845 | 49 (46) | 22 (21) | 78 kDa glucose-regulated protein homolog | X | ER-specific O-GlcNAc (eOGT, EGF repeat-specific O-GlcNAc-transferase)? |
HSP70_PLAFA | 1889 | 0.31 | 74,754 | 66 (59) | 21 (20) | Heat shock 70 kDa protein = 2 | X | [59] (human breast cancer cell line MCF7); [49] (human hepatocarcinoma derived cell line HepG2) |
HXK_PLAFA | 38 | 0.07 | 56,166 | 4 (1) | 3 (1) | Hexokinase | No previous report | |
OAT_PLAFD | 519 | 0.19 | 46,938 | 15 (10) | 9 (6) | Ornithine aminotransferase | No previous report | |
PGK_PLAF7 | 562 | 0.29 | 45,569 | 21 (21) | 11 (11) | Phosphoglycerate kinase | [57] (Rattus norvegicus) | |
sWGA | ||||||||
MYOA_PLAFB | 224 | 0.08 | 93,017 | 10 (5) | 7 (2) | Myosin-A | ||
KC1_PLAF4 | 69 | 0.09 | 38,036 | 5 (3) | 3 (1) | Casein kinase I | No previous report | |