Table 4 Frequency distribution of CYP2D6 star alleles
Variant | Friedrich et al. [19] (n = 474) | Current study | ||
|---|---|---|---|---|
Total (n = 380) | Recurrence (n = 88) | No recurrence (n = 292) | ||
*1 | 0.418 | 0.409 | 0.409 | 0.456 |
*2 | 0.253 | 0.220 | 0.148 | 0.241 |
*4 | 0.112 | 0.086 | 0.102 | 0.082 |
*5 | 0.027 | 0.024 | 0.068 | 0.010 |
*9 | 0.011 | 0.008 | 0.00 | 0.010 |
*10 | 0.015 | 0.050 | 0.045 | 0.051 |
*17 | 0.055 | 0.018 | 0.034 | 0.014 |
*29 | 0.023 | 0.013 | 0.000 | 0.017 |
*35 | 0.023 | 0.00 | 0.000 | 0.000 |
*39 | 0.015 | 0.060 | 0.102 | 0.048 |
*41 | 0.042 | 0.047 | 0.068 | 0.041 |
Other | 0.000 | 0.024 | 0.023 | 0.024 |
Activity score (phenotype)b | ||||
0 | – | – | 0.023 | 0.027 |
0.5 | – | – | 0.023 | 0.027 |
1 | – | – | 0.295 | 0.151 |
1.5 | – | – | 0.182 | 0.137 |
2 | – | – | 0.341 | 0.575 |
> 2 | – | – | 0.136 | 0.082 |