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Table 2 Number of significant SNPs and genes in each subpopulation compared to ancestral artemisinin sensitive subpopulation

From: Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia

Subpopulations

Number of isolates

Number of significant SNPs

Number of significant genes

KH1.2

5

1361

823

KH2.1

11

1620

938

KH2.2

22

2312

1125

KH3

12

1495

859

KH4

9

1891

978

KH5

14

1612

900

KHA

49

740

493

  1. Significant SNPs were described using one tailed Fisher-exact test. For each SNP the ALT frequency in each subpopulation was compared to the ALT frequency in KH1.1 (45 isolates) to calculate the p value. SNPs with p value ≤ 0.05 were considered as significant and the genes containing these SNPs are considered as the significant genes in each subpopulation
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Malaria Journal

ISSN: 1475-2875

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