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Table 3 Baseline stability of Plasmodium HRP2, pLDH, and aldolase in non-stabilized samples (study positive controls) during the 53 weeks of analysis

From: Stabilization of RDT target antigens present in dried Plasmodium falciparum-infected samples for validating malaria rapid diagnostic tests at the point of care

Sample type Parasite concentration Malaria RDTs HRP 2 pLDH and aldolase
Reactivity (in weeks) Percentage stability Reactivity (in weeks) Percentage stability
Culture Sample 2000 P/µL SD Bioline 24 45.28 12 22.64
First Response 24 45.28 12 22.64
BinaxNOW 24 45.28 18 33.96
500 P/µL SD Bioline 24 45.28 6 11.32
First Response 24 45.28 6 11.32
BinaxNOW 24 45.28 2 3.77
200 P/µL SD Bioline 24 45.28 0 0.00
First Response 24 45.28 0 0.00
BinaxNOW 24 45.28 0 0.00
Patient Sample 2000 P/µL SD Bioline 24 45.28 12 22.64
First Response 21 39.62 12 22.64
BinaxNOW 24 45.28 2 3.77
500 P/µL SD Bioline 24 45.28 4 7.55
First Response 21 39.62 2 3.77
BinaxNOW 21 39.62 2 3.77
200 P/µL SD Bioline 24 45.28 0 0.00
First Response 24 45.28 0 0.00
BinaxNOW 24 45.28 0 0.00
  1. P/µL, Parasites per microliter; RDTs, rapid diagnostic Tests; pLDH, Plasmodium lactate dehydrogenase; HRP2, histidine rich protein II
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Malaria Journal

ISSN: 1475-2875

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