Malaria Journal

Table 4 Limits of stabilization (in weeks) for each chemical additive at different parasite densities; on improving the stability of HRP2, pLDH and aldolase present in dried P. falciparum-infected samples

From: Stabilization of RDT target antigens present in dried Plasmodium falciparum-infected samples for validating malaria rapid diagnostic tests at the point of care

Chemical additives	HRP2						pLDH and aldolase
	2000 P/µL		500 P/µL		200 P/µL		2000 P/µL		500 P/µL
	Stability (in weeks)	Percentage stability (%)	Stability (in weeks)	Percentage stability (%)	Stability (in weeks)	Percentage stability (%)	Stability (in weeks)	Percentage stability (%)	Stability (in weeks)	Percentage stability (%)
Sucrose	53	100	53	100	33	62	21	40	0	0
Glycerol/sucrose	33	62	33	62	21	40	18	34	18	34
Alsever’s/sucrose	53	100	53	100	53	100	12	23	2	4
Biostab/sucrose	53	100	53	100	53	100	2	4	2	4
Trehalose	53	100	53	100	43	81	43	81	21	40
Sucrose/trehalose	53	100	43	81	33	62	53	100	18	34
Glycerol/trehalose	53	100	24	45	24	45	12	23	10	19
Biostab/trehalose	53	100	53	100	53	100	24	45	2	4
LDH stabilizer	53	100	53	100	33	62	15	28	2	4
LDH stabilizer/trehalose	43	81	43	81	33	62	24	45	10	19

P/µL, Parasites per microliter; pLDH, Plasmodium lactate dehydrogenase; HRP2, histidine rich protein II

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ISSN: 1475-2875

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