Table 1 Single nucleotide polymorphisms (SNPs) in the gene encoding lactate dehydrogenase (LDH) of Plasmodium falciparum
From: Global sequence diversity of the lactate dehydrogenase gene in Plasmodium falciparum
| Allele | Isoform | Nucleotide position (corresponding amino acid position) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
36 (12) |
73 (25) |
85 (29) |
259 (87) |
399 (133) |
407 (136) |
450 (150) |
451 (151) |
513 (171) |
560 (187) |
563 (188) |
783 (261) |
814 (272) |
858 (286) |
891 (297) | ||
| L1a | LDH-1 |
TCA S |
CAG Q |
GGA G |
GGA G |
GTA V |
TTA L |
TTA L |
GGT G |
CCA P |
GTT V |
CTT L |
TCA S |
GAT D |
GTT V |
GAG E |
| L1b |
TCG S | – | – | – | – | – | – | – | – | – | – | – | – | – |
GAA E | |
| L1c | – | – | – | – | – | – | – | – |
CCC P | – | – | – | – |
GTC V | – | |
| L1d | – | – | – | – | – | – |
TTG L | – | – | – | – | – | – | – | – | |
| L1e | – | – | – | – | – | – | – | – | – | – | – |
TCG S | – | – | – | |
| L2 | LDH-2 | – | – | – | – | – | – | – | – | – | – | – | – |
AAT N | – | – |
| L3 | LDH-3 | – |
AAG K | – | – | – | – | – | – | – | – | – | – | – | – | – |
| L4 | LDH-4 | – | – |
CGA R |
CGA R |
GTC V | – | – |
CGT R | – |
GGT G | – | – | – | – | – |
| L5 | LDH-5 | – | – | – | – | – |
TCA S | – | – | – | – |
CCT P | – | – | – | – |