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Table 2 Geographical distribution of ldh alleles in natural isolates of Plasmodium falciparum

From: Global sequence diversity of the lactate dehydrogenase gene in Plasmodium falciparum

Origin of P. falciparum L1a L1b L1c L1d L1e L2 L3 L4 L5
LDH-1 LDH-2 LDH-3 LDH-4 LDH-5
Cambodiac 1 0 0 0 0 0 0 0 0
P. R. Chinac 0 0 0 1 0 1 0 1 1
Indonesiaa 0 (133)d 0 0 0 0 0 0 0 0
Indiaa 2 (46)d 0 1 0 0 0 0 0 0
Irana 6 1 0 0 0 0 0 0 0
Laosc 2 0 0 0 0 0 0 0 0
Malaysiac 1 0 0 0 0 0 0 0 0
The Philippinesc 1 0 0 0 0 0 0 0 0
Thailandb 53 0 0 0 0 0 0 0 0
Vietnamc 3 0 0 0 0 0 0 0 0
The Gambiac 54 0 0 0 0 11 0 0 0
Ghanac 0 0 0 0 0 1 0 0 0
Madagascara 0 (126)d 0 0 0 0 1 1 0 0
Malic 14 0 0 0 1 8 0 0 0
Mozambiquec 1 0 0 0 0 0 0 0 0
Senegalc 54 0 0 0 0 8 0 0 0
Tanzaniac 1 0 0 0 0 0 0 0 0
Ugandac 7 0 0 0 0 1 0 0 0
Brazilc 4 0 0 0 0 0 0 0 0
Columbiac 1 0 0 0 0 0 0 0 0
El Salvadorc 1 0 0 0 0 0 0 0 0
French Guianac 22 0 0 0 0 0 0 0 0
Hondurasc 2 0 0 0 0 0 0 0 0
Total 230 1 1 1 1 31 1 1 1
  1. The numbers of nucleotide sequences from the PlasmoDB and NCBI databases are shown
  2. aPublished sequences of P. falciparum ldh in Indonesia, Madagascar, India and Iran were taken from the literature [11,12,13, 39]
  3. bSequence data of 50 P. falciparum isolates in the present study and 3 sequences of P. falciparum strain K1 submitted to the NCBI database
  4. cUnpublished nucleotide sequences of the ldh gene were retrieved from the PlasmoDB and NCBI databases and used to deduce the amino acid sequences (see Additional file 2)
  5. dNumbers in brackets indicate ldh sequences of P. falciparum that were identical to L1a of P. falciparum 3D7 which were reported in literature [11,12,13, 39], but without the NCBI sequence IDs