Mutant alleles in Pfdhfr genea
|
Number of the isolates, n (%)
|
Mutant alleles in Pfdhps geneb
|
Number of the isolates, n (%)
|
---|
N51I
|
41/48 (85.4)
|
A437G
|
48/48 (100.0)
|
C59R
|
29/48 (60.4)
|
K540E
|
1/48 (2.1)
|
S108N
|
48/48 (100.0)
|
A581G
|
1/48 (2.1)
|
- aPfdhfr polymorphisms: codon 51, asparagine to isoleucine; codon 59, cysteine to arginine; codon 108, serine to asparagine
- bPfdhps polymorphisms: codon 437, alanine to glycine; codon 540, lysine to glutamic acid; codon 581, alanine to glycine