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Table 2 Types of mutant Pfdhfr and Pfdhps haplotypes among 48 Plasmodium falciparum isolates

From: Molecular identification of sulfadoxine-pyrimethamine resistance in malaria infected women who received intermittent preventive treatment in the Democratic Republic of Congo

Haplotype

Pfdhfr genea

Number of the isolates, n (%)

Pfdhps geneb

Number of the isolates, n (%)

Wild-type

CNCSI

0/48 (0.0)

SAKAA

0/48 (0.0)

Triple

CIRNI

23/48 (47.9)

SGEGA

1/48 (2.1)

Double

CICNI

18/48 (37.5)

–

–

Double

CNRNI

6/48 (12.5)

–

–

Single

CNCNI

1/48 (2.1)

SGKAA

47/48 (97.9)

  1. aPfdhfr wild-type haplotype (CNCSI [C50/N51/C59/S108/I164]); triple (51I/59R/108N); double (51I/108N, or 59R/108N); and single (108N) mutant
  2. bWild-type Pfdhps haplotype (SAKAA [S436/A437/K540/A581/A613]); triple (437G/540E/581G); and single (437G) mutant