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Table 2 Summary statistics of maximal change from pre-dose in QTcF (safety analysis set)

From: A phase 1 evaluation of the pharmacokinetic/pharmacodynamic interaction of the anti-malarial agents KAF156 and piperaquine

Treatment Statistics QTcF change from pre-dose (msec)
KAF156 800 mg + PPQ 1280 mg N 24
Mean (SD) 12.5 (7.84)
CV% 62.51
Median 13.7
(Min, max) (− 8.7, 26.00)
KAF156 800 mg N 24
Mean (SD) 10.8 (9.83)
CV% 91.18
Median 8.0
(Min, max) (− 1.7, 44.00)
PPQ 1280 mg N 24
Mean (SD) 8.2 (8.29)
CV% 101.63
Median 7.0
(Min, max) (− 7.3, 23.67)
  1. QTcF = Maximum change from post treatment in QTcF