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Table 2 Summary statistics of maximal change from pre-dose in QTcF (safety analysis set)

From: A phase 1 evaluation of the pharmacokinetic/pharmacodynamic interaction of the anti-malarial agents KAF156 and piperaquine

Treatment

Statistics

QTcF change from pre-dose (msec)

KAF156 800 mg + PPQ 1280 mg

N

24

Mean (SD)

12.5 (7.84)

CV%

62.51

Median

13.7

(Min, max)

(− 8.7, 26.00)

KAF156 800 mg

N

24

Mean (SD)

10.8 (9.83)

CV%

91.18

Median

8.0

(Min, max)

(− 1.7, 44.00)

PPQ 1280 mg

N

24

Mean (SD)

8.2 (8.29)

CV%

101.63

Median

7.0

(Min, max)

(− 7.3, 23.67)

  1. QTcF = Maximum change from post treatment in QTcF