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Table 1 Summary of CYP2D6 phenotype activity score estimations

From: Primaquine ineligibility in anti-relapse therapy of Plasmodium vivax malaria: the problem of G6PD deficiency and cytochrome P-450 2D6 polymorphisms

  1. Activity scores for each component allele in the genotype (allele 1 and allele 2) sum to give the genotype activity scores. Phenotypes with AS ≤ 1.0 (in red) are considered to be poor primaquine metabolizers (J. Kevin Baird, personal communication, 2017). The italic data was to differentiate the allele-level from phenotype-level activity scores. The colour gradient represented the spectrum of activity scores from very low to very high