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Fig. 5 | Malaria Journal

Fig. 5

From: A novel immortalized hepatocyte-like cell line (imHC) supports in vitro liver stage development of the human malarial parasite Plasmodium vivax

Fig. 5

Immortalized hepatocyte-like cells (imHCs) were susceptible to Plasmodium vivax liver-stage infection. Size distributions of P. vivax exoerythocytic forms (EEs) on days 4 and 7 post-infection in HC-04 cells (a) and imHCs (b). Representative immunofluorescence images of the intracellular P. vivax EEs on days 4 and 7 post-infection (c). Plasmodium vivax EEs in imHCs were visualized using an indirect immunofluorescence assay with antibodies against parasite UIS4 (red) and HSP70 (green). The nuclei were counter-stained with DAPI (blue). Scale bar = 10 μm

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