Table 1 Baseline characteristics of patients admitted to the study
AS–AQ (N = 217) | DHA–PPQ (N = 218) | AM–LM (N = 218) | p | ||||
|---|---|---|---|---|---|---|---|
Age (months)—median [IQR] | 29 | [18–41] | 29 | [18–39] | 30 | [21–39] | 0.898 |
Sex ratio (M/F) | 1.1 | (115/102) | 1.2 | (118/100) | 1.1 | (112/106) | 0.846 |
Weight—median [IQR] | 10.2 | [8.5–12.5] | 10.5 | [9.1–12.1] | 10.5 | [8.7–12.3] | 0.975 |
Weight Z-score—mean (SD) | − 0.85 | (0.92) | − 0.85 | (0.87) | − 0.97 | (0.89) | 0.324 |
Axillary temperature °C—mean (SD) | 39.0 | (1.1) | 39.0 | (1.1) | 38.9 | (1.1) | 0.666 |
Temperature ≥ 37.5 °C—n (%) | 194 | (89.4) | 197 | (90.4) | 197 | (90.4) | 0.927 |
Temperature ≥ 38.5 °C—n (%) | 152 | (70.1) | 158 | (72.5) | 150 | (68.8) | 0.694 |
Parasite density/µL—median [IQR] | 34,915 | [9822–77,185] | 41,042 | [14,118–85,926] | 46,506 | [13,776–98,311] | 0.111 |
Presence of gametocytes—n (%) | 11 | (5.1) | 5 | (2.3) | 9 | (4.2) | 0.307 |
Haemoglobin (g/dL)—mean (SD) | 9.5 | (1.6) | 9.7 | (1.7) | 9.7 | (1.7) | 0.286 |
Haemoglobin < 8 g/dL—n (%) | 45 | (20.7) | 35 | (16.1) | 40 | (18.4) | 0.452 |