Fig. 10

Influence of cost of resistance on time-to-resistance for mixtures and sequences. Row 1 (a, b) same as Fig. 6 with no cost of resistance, row 2 (c, d) cost of resistance set to 0.15 with dominance of cost set to 0.5. The ‘s’ and ‘m’ on the upper X axis and mix/seq in the lower right of each panel stand for sequence and mixture and are explained in the legend to Fig. 6. The increase in cost of resistance from a to c removes the advantage of sequence relative to mixture. The ratio of time-to-resistance for the mixture divided by that for the sequence goes from 0.8 to 1. Costs seem to favour mixtures in these plots. Also be aware that costs would lead to a decline in the frequency of resistance for the first insecticide in a sequence when it stops being used