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Fig. 9 | Malaria Journal

Fig. 9

From: Insecticide resistance evolution with mixtures and sequences: a model-based explanation

Fig. 9

Influence of starting frequencies of resistance on time-to-resistance for mixtures and sequences. Starting frequency of the gene conferring resistance to insecticide 1 is decreased from row 1 (a, b) to row 2 (c, d). Effectiveness of insecticide 1 is increased from column 1 (a, c) to column 2 (b, d). The ‘s’ and ‘m’ on the upper X axis and mix/seq in the lower right of each panel stand for sequence and mixture and are explained in the legend to Fig. 6. a All control inputs equal at 0.5, starting frequencies of resistance at 0.01, b effectiveness for insecticide 1 increased from 0.5 to 0.8, c starting frequency of resistance for insecticide 1 decreased from 0.01 to 0.001, d effectiveness for insecticide 1 increased from 0.5 to 0.8 and starting frequency for insecticide 1 decreased from 0.01 to 0.001. In these scenarios the starting frequencies do not change better performance of sequences at low effectiveness and mixtures at high effectiveness

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