From: Insecticide resistance evolution with mixtures and sequences: a model-based explanation
Parameter to increase | Effect on resistance evolution | Mechanism |
---|---|---|
1. Effectiveness | Faster | Reduced fitness of SS and SR exposed to insecticide |
2. Exposure | Faster | Reduced fitness of SS and SR overall |
3. Dominance of resistance | Faster | Increased fitness of SR exposed to insecticide |
4. Resistance restoration | Faster | Increased fitness of RR and SR exposed to insecticide |
5. Frequency | Faster | Less change needed to reach resistance threshold |
6. Cost of resistance | Slower | Reduced fitness of RR and SR not exposed to insecticide |